Effect of lower esophageal sphincter tone and crural diaphragm contraction on distensibility of the gastroesophageal junction in humans.

@article{Shaker2004EffectOL,
  title={Effect of lower esophageal sphincter tone and crural diaphragm contraction on distensibility of the gastroesophageal junction in humans.},
  author={Reza Shaker and Eytan Bardan and Chengming Gu and Benson T. Massey and Thomas Sanders and Mark K. Kern and Raymond G. Hoffmann and Walter J. Hogan},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2004},
  volume={287 4},
  pages={G815-21}
}
Previous studies of distensibility of the gastroesophageal junction (GEJ) in humans have not tried to distinguish between the effects of muscle action and passive elastic tissue properties of the GEJ. We studied 15 healthy subjects (ages 23-67 yr, 11 men/4 women) by using a catheter with a highly complaint bag positioned manometrically at the GEJ. The bag was distended with air at a rate of 20 ml/min while intrabag pressure was recorded. Distensions were performed during normal breathing, with… CONTINUE READING