Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue.

Abstract

PURPOSE Nuclear receptor coactivator expression and activity may partly explain the complex agonist/antagonist effects of tamoxifen at clinical level. In a preoperative trial, dose reduction from 20 to 1 mg tamoxifen was associated with retained antiproliferative effect on breast cancer. Here, we assessed the gene expression of the steroid receptor… (More)
DOI: 10.1158/1078-0432.CCR-09-1859

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@article{Moi2010EffectOL, title={Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue.}, author={Line L. Haugan Moi and Marianne Hauglid Fl{\aa}geng and Sara Gandini and Aliana Guerrieri-gonzaga and Bernardo Bonanni and Matteo Lazzeroni and Jennifer Gjerde and Ernst Asbj\orn Lien and Andrea U. Decensi and Gunnar Mellgren}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2010}, volume={16 7}, pages={2176-86} }