Effect of low concentrations of K+ and Cl− on the Na+-dependent neuronal uptake of [3H] dopamine


The specific uptake of [3H] dopamine (DA) was studied using a crude synaptosomal fraction obtained from rat striatum. In a medium containing a 10 mM NaHC03/NaH2PO4 buffer and no added K+ ions, addition of NaCl elicited an increase in DA uptake for Na+ concentrations from 10 to 60 mM, and then a decrease of uptake for Na+ concentrations up to 130 mM. These… (More)
DOI: 10.1007/BF00167179

6 Figures and Tables


  • Presentations referencing similar topics