Effect of low‐carbohydrate diet on markers of renal function in patients with type 2 diabetes: A meta‐analysis

@article{Suyoto2018EffectOL,
  title={Effect of low‐carbohydrate diet on markers of renal function in patients with type 2 diabetes: A meta‐analysis},
  author={Perdana Samekto Tyasnugroho Suyoto},
  journal={Diabetes/Metabolism Research and Reviews},
  year={2018},
  volume={34}
}
  • P. S. Suyoto
  • Published 3 July 2018
  • Medicine
  • Diabetes/Metabolism Research and Reviews
Meta‐analysis was conducted to clarify the effect of low‐carbohydrate diet (LCD) on renal function in patients with type 2 diabetes. An extensive literature search was conducted on scientific databases including PubMed, Scopus, and Cochrane Library until September 2017. Only controlled trials on human subjects written in English were included in this meta‐analysis. Several markers of renal function were compared between subjects who adopted an LCD or control diet, including estimated glomerular… 
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References

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Impact of low-carbohydrate diet on renal function: a meta-analysis of over 1000 individuals from nine randomised controlled trials
TLDR
In the present meta-analysis, it is identified that the increase in eGFR was greater in LCD compared with the control diet in overweight and obese individuals without CKD.
Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: A systematic review and meta-analysis of randomized controlled trials.
TLDR
The results suggested a beneficial effect of LCD intervention on glucose control in patients with type 2 diabetes, and a positive effect on triglycerides and HDL cholesterol concentrations, but without significant effect on long term weight loss.
Comparison of High vs. Normal/Low Protein Diets on Renal Function in Subjects without Chronic Kidney Disease: A Systematic Review and Meta-Analysis
TLDR
HP diets were associated with increased GFR, serum urea, urinary calcium excretion, and serum concentrations of uric acid, which should be handled with caution in the light of the high risk of kidney disease among obese.
Long-Term Effects of a Very Low Carbohydrate Compared With a High Carbohydrate Diet on Renal Function in Individuals With Type 2 Diabetes
TLDR
Compared with a traditional HC weight loss diet, consumption of an LC high protein diet does not adversely affect clinical markers of renal function in obese adults with T2DM and no preexisting kidney disease.
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TLDR
Meta-regression analyses show that hemoglobin A1c, fasting glucose, and some lipid fractions (triglycerides) improved with lower carbohydrate-content diets, and overall effect on weight was equivocal among the studies evaluated in this meta-analysis.
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TLDR
A systematic review and meta‐analysis showed the LCD to be associated with significant decreases in body weight, as well as an increase in high‐density lipoprotein cholesterol and creatinine, whereas limited data exist concerning plasma uric acid.
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TLDR
Low-carbohydrate diets were associated with a significantly higher risk of all-cause mortality and they were not significantly associated with the risk of CVD mortality and incidence.
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TLDR
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TLDR
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TLDR
Reducing dietary carbohydrate may produce clinical improvements in the management of type 2 diabetes and further research is needed to understand the true effect of dietary carbohydrate restriction on HbA1c.
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