Effect of lossy compression of quality scores on variant calling

@article{Ochoa2016EffectOL,
  title={Effect of lossy compression of quality scores on variant calling},
  author={Idoia Ochoa and Mikel Hernaez and Rachel L. Goldfeder and Tsachy Weissman and Euan Ashley},
  journal={Briefings in bioinformatics},
  year={2016},
  volume={18 2},
  pages={
          183-194
        }
}
Recent advancements in sequencing technology have led to a drastic reduction in genome sequencing costs. This development has generated an unprecedented amount of data that must be stored, processed, and communicated. To facilitate this effort, compression of genomic files has been proposed. Specifically, lossy compression of quality scores is emerging as a natural candidate for reducing the growing costs of storage. A main goal of performing DNA sequencing in population studies and clinical… CONTINUE READING
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

Similar Papers

Loading similar papers…