Effect of loperamide and naloxone on mouth-to-caecum transit time evaluated by lactulose hydrogen breath test.

@article{Basilisco1985EffectOL,
  title={Effect of loperamide and naloxone on mouth-to-caecum transit time evaluated by lactulose hydrogen breath test.},
  author={Guido Basilisco and A. Bozzani and Gabriella Camboni and Martino Recchia and Maurizio Quatrini and Diletta Conte and Roberto Penagini and Paolo A. Bianchi},
  journal={Gut},
  year={1985},
  volume={26 7},
  pages={700-3}
}
The effect of loperamide and naloxone on mouth-to-caecum transit time was evaluated by the lactulose hydrogen breath test in four men and four women. Each subject underwent tests during the administration of placebo, loperamide (12-16 mg po), naloxone (40 micrograms/kg/h by a three-hour intravenous infusion), and loperamide plus naloxone, carried out at intervals of one or two weeks. The transit time was significantly longer after loperamide, and this effect was antagonised by the concomitant… CONTINUE READING