Effect of long-term ethanol exposure on the acinar distribution of hepatic glutathione S-transferase.

@article{Vanhaecke2000EffectOL,
  title={Effect of long-term ethanol exposure on the acinar distribution of hepatic glutathione S-transferase.},
  author={Tamara Vanhaecke and Kai O. Lindros and Teija Oinonen and Antoine Vercruysse and Vera Rogiers},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  year={2000},
  volume={28 12},
  pages={1470-4}
}
The ability of ethanol to affect the regional distribution of individual glutathione S-transferase (GST) isoenzymes in rat liver was investigated by analyzing the expression levels in cell lysates obtained from the periportal or perivenous liver region after in situ digitonin perfusion. In control rats, a significant perivenous dominance of GST proteins and… CONTINUE READING