• Corpus ID: 42359475

Effect of long term estrogen and lithium treatment on restraint induced gastric erosion in intact and ovariectomized rats.

  title={Effect of long term estrogen and lithium treatment on restraint induced gastric erosion in intact and ovariectomized rats.},
  author={M S Abouzeit-Har and T. Verimer and John Paul Long},
  journal={Die Pharmazie},
  volume={37 8},
Gastric erosions were induced in intact and ovariectomized rats by subjecting them to 24 h restraint. In association with erosion, histidine decarboxylase was determined in the glandular portion of the stomach. Under these experimental conditions, 8 weeks ovariectomy significantly reduced the severity of restraint induced gastric erosions. Administration of estradiol benzoate 10 micrograms/d for 4 weeks before restraint did not influence the severity of the erosions in either the control or… 
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