Effect of long-term captopril therapy on left ventricular remodeling and function during healing of canine myocardial infarction.


To determine whether the long-term reduction of preload and afterload by captopril during healing after acute anterior myocardial infarction might attenuate left ventricular remodeling and improve function, 30 chronically instrumented dogs with infarction produced by left anterior descending coronary artery ligation were randomized 2 days later to oral… (More)


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