Effect of long-term administration of progestogen on post-menopausal bone loss: result of a two-year, controlled randomized study.


OBJECTIVE We determined whether a progestogen given alone to post-menopausal women may prevent bone loss. STUDY DESIGN Thirty-five early post-menopausal women who had not received any form of treatment to prevent bone loss were randomly assigned to a 2-year regimen of 500 micrograms/day of a gestagen derived from 19-norprogesterone (Promegestone) or a… (More)