Effect of long-term administration of beta-carotene on lymphocyte subsets in humans.

@article{Murata1994EffectOL,
  title={Effect of long-term administration of beta-carotene on lymphocyte subsets in humans.},
  author={Takuji Murata and Hiroshi Tamai and Takao Morinobu and Mitsuhiro Manago and Hiroyuki Takenaka and Kunioki Hayashi and Makoto Mino},
  journal={The American journal of clinical nutrition},
  year={1994},
  volume={60 4},
  pages={597-602}
}
To examine whether or not beta-carotene alters immune indexes, we performed a single-blind trial in healthy male nonsmokers. Lymphocyte subsets were assessed by double labeling with monoclonal antibodies before and after 44 wk of administration of either beta-carotene (60 mg/d; n = 10) or placebo (n = 10). In addition, we measured the beta-carotene concentrations in plasma, mononuclear cells (MNC), platelets, and red blood cells (RBCs), as well as the plasma alpha-tocopherol concentration. An… CONTINUE READING

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