Effect of local infusion of glutamate analogues into the nucleus accumbens of rats: an electrochemical and behavioural study.

@article{Svensson1994EffectOL,
  title={Effect of local infusion of glutamate analogues into the nucleus accumbens of rats: an electrochemical and behavioural study.},
  author={Lena Svensson and Jing-xing Zhang and Kenn Johannessen and J{\"o}rgen A. Engel},
  journal={Brain research},
  year={1994},
  volume={643 1-2},
  pages={155-61}
}
In vivo voltammetry at electrochemically pretreated carbon fibre electrodes was used to investigate the effect of local infusion of glutamate analogues on dopamine (DA) release in rat nucleus accumbens. Infusion of a low dose of NMDA or AMPA (1 mM/0.2 microliter), but not L-glutamate or kainate, was followed a few minutes later by a large but short-lived increase in the extracellular concentration of DA. The involvement of spreading depression was indicated since this response could be repeated… CONTINUE READING

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