Effect of liposomal-encapsulated superoxide dismutase on active oxygen-related human disorders. A preliminary study.

@article{Niwa1985EffectOL,
  title={Effect of liposomal-encapsulated superoxide dismutase on active oxygen-related human disorders. A preliminary study.},
  author={Yasuhiro Niwa and Kyoichi Somiya and Alan M. Michelson and K Puget},
  journal={Free radical research communications},
  year={1985},
  volume={1 2},
  pages={137-53}
}
Liposomal-encapsulated superoxide dismutase was clinically applied to patient showing an increase in neutrophil active oxygen generation, and those with diseases such as severe rheumatoid arthritis (RA), Crohn's disease and progressive systemic sclerosis (PSS) in which presence of a plasmatic clastogenic factor has been demonstrated. Liposomal SOD injection (2.5 mg twice a week) resulted in marked remission in 12 out of 16 patients with active Behcet's disease. The drug was impressively… CONTINUE READING