Effect of lipid types on physicochemical characteristics, stability and antioxidant activity of gamma-oryzanol-loaded lipid nanoparticles.

@article{Ruktanonchai2009EffectOL,
  title={Effect of lipid types on physicochemical characteristics, stability and antioxidant activity of gamma-oryzanol-loaded lipid nanoparticles.},
  author={Uracha Rungsardthong Ruktanonchai and Usawadee Sakulkhu and Piyawan Bejrapha and Praneet Opanasopit and Nuntavan Bunyapraphatsara and Varaporn Buraphacheep Junyaprasert and Satit Puttipipatkhachorn},
  journal={Journal of microencapsulation},
  year={2009},
  volume={26 7},
  pages={614-26}
}
In the present study gamma-oryzanol, an antioxidant, was incorporated into three different types of solid lipid: wax, triglycerides, a mixture of glycerides as solid lipid nanoparticles (SLN) and liquid lipid (Miglyol 812) as nanoemulsion (NE). Instability was found only from NE due to its significant increase in particle size and decreased entrapment efficiency (%EE) at a storage temperature of 45 degrees C. Solid lipid type in SLN plays an important role only on %EE, but not chemical… CONTINUE READING