Effect of levetiracetam in refractory childhood epilepsy syndromes.

@article{Lagae2003EffectOL,
  title={Effect of levetiracetam in refractory childhood epilepsy syndromes.},
  author={Lieven Lagae and Gunnar Buyse and Arlette Deconinck and Berten Ceulemans},
  journal={European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society},
  year={2003},
  volume={7 3},
  pages={123-8}
}
In this open-label add-on study of levetiracetam in refractory childhood epilepsy syndromes, we studied the effect of a rapid introduction of levetiracetam on the total seizure frequency in 21 children, known to have partial and generalized seizures. Starting dosage was 10 mg/kg/day, increased every 4th day by 10 mg/kg up to a maximum of 60 mg/kg/day, depending on efficacy and tolerability. In this highly refractory population, 47% showed a seizure frequency reduction of more than 50… CONTINUE READING

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Levetiracetam was effective both in partial and generalized seizures , with a significant effect on myoclonic seizures .
Levetiracetam was effective both in partial and generalized seizures , with a significant effect on myoclonic seizures .
Levetiracetam was effective both in partial and generalized seizures , with a significant effect on myoclonic seizures .
Levetiracetam was effective both in partial and generalized seizures , with a significant effect on myoclonic seizures .
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