Effect of leukocytic endogenous mediator (LEM) on zinc absorption in the rat.

@article{Pekarek1976EffectOL,
  title={Effect of leukocytic endogenous mediator (LEM) on zinc absorption in the rat.},
  author={R. S. Pekarek and Gary W. Evans},
  journal={Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine},
  year={1976},
  volume={152 4},
  pages={573-5}
}
Leukocytic endogenous mediator (LEM) was shown to produce a significant increase in the intestinal absorption of zinc within 7 hr after its administration to normal rats. Consistent with earlier studies, LEM also produced a significant decrease in the plasma zinc concentration and an increased hepatic uptake of this metal which further demonstrates that LEM may be a key intermediate in altering zinc homeostasis during inflammation. 

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