Effect of isoproterenol on amino acid levels and protein turnover in skeletal muscle.

@article{Li1977EffectOI,
  title={Effect of isoproterenol on amino acid levels and protein turnover in skeletal muscle.},
  author={Jeanne B Li and Leonard S. Jefferson},
  journal={The American journal of physiology},
  year={1977},
  volume={232 2},
  pages={E243-9}
}
The effect of isoproterenol on amino acid concentrations in perfusate and skeletal muscle was studied during a 3-h perfusion of the isolated rat hemicorpus. The beta-adrenergic agonist inhibited the accumulation of alanine, threonine, phenylalanine, tyrosine, lysine, arginine, leucine, and valine and increased the loss of glutamate, aspartate, serine, and isoleucine from the pool of free amino acids in perfusate and muscle. The loss of glutamate was accompanied by a greater accumulation of… CONTINUE READING