Effect of ischemic preconditioning on myocardial protection in coronary artery bypass graft patients : can the free radicals act as a trigger for ischemic preconditioning?

@article{Wu2001EffectOI,
  title={Effect of ischemic preconditioning on myocardial protection in coronary artery bypass graft patients : can the free radicals act as a trigger for ischemic preconditioning?},
  author={Zhongkai Wu and Matti R. Tarkka and Jack Eloranta and Erkki J Pehkonen and Liisa Kaukinen and Eva Liisa Honkonen and S. Kaukinen},
  journal={Chest},
  year={2001},
  volume={119 4},
  pages={1061-8}
}
OBJECTIVE To investigate the interrelationship of free radicals (FRs), ischemic preconditioning (IP), and hemodynamic function in coronary artery bypass graft (CABG) patients. DESIGN Prospective, randomized, and controlled clinical study. PATIENTS Forty CABG patients were randomized into an IP group (n = 20) and a control group (n = 20). INTERVENTION The IP group was preconditioned with two cycles of two-min ischemia followed by 3-min reperfusion before cross-clamping. MEASUREMENT AND… CONTINUE READING