Effect of ischemia, hypertrophy, hypoxia, acidosis, and alkalosis on canine defibrillation.

@article{Kerber1983EffectOI,
  title={Effect of ischemia, hypertrophy, hypoxia, acidosis, and alkalosis on canine defibrillation.},
  author={Richard E. Kerber and Natesa G. Pandian and Robert Hoyt and Steven R. Jensen and Samon Koyanagi and Joseph Grayzel and R A Kieso},
  journal={The American journal of physiology},
  year={1983},
  volume={244 6},
  pages={H825-31}
}
Our purpose was to assess the effect of myocardial ischemia, left ventricular hypertrophy, and systemic hypoxia and acid-base abnormalities on the energy requirements for defibrillation. We determined the defibrillation threshold (DFT), the minimum energy required to defibrillate. DFT was not significantly elevated after left anterior descending coronary occlusion, nor was there a relationship between the size of the occluded coronary distribution area (coronary risk area) and the change in DFT… CONTINUE READING
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