Effect of iontophoresis on in vitro transdermal absorption of almotriptan.

Abstract

The aim of the present work was to characterize the in vitro transdermal absorption of almotriptan through pig ear skin. The passive diffusion of almotriptan malate and its iontophoretic transport were investigated using current densities of 0.25 and 0.50mA/cm(2). In vitro iontophoresis experiments were conducted on diffusion cells with an agar bridge… (More)
DOI: 10.1016/j.ijpharm.2011.06.039

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