Effect of ionophore antibiotics on experimentally induced lactic acidosis in cattle.

@article{Nagaraja1985EffectOI,
  title={Effect of ionophore antibiotics on experimentally induced lactic acidosis in cattle.},
  author={T G Nagaraja and T B Avery and S J Galitzer and David L. Harmon},
  journal={American journal of veterinary research},
  year={1985},
  volume={46 12},
  pages={2444-52}
}
Salinomycin, a new ionophore antibiotic, was tested and compared with lasalocid and monensin for preventing experimentally induced lactic acidosis. Five rumen-fistulated adult cattle were used in a 5 X 5 Latin square design, and the treatments were as follows: no treatment (control), 0.11 mg of salinomycin/kg of body weight (S1), 0.22 mg of salinomycin/kg (S2), 0.66 of lasalocid/kg, and 0.66 mg of monensin/kg. Acidosis was induced by intraruminal administration of a ground corn-corn starch… CONTINUE READING