Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae.

@article{Kyaw2006EffectOI,
  title={Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae.},
  author={Moe H Kyaw and Ruth Lynfield and William Schaffner and Allen S. Craig and James L Hadler and Arthur L. Reingold and Ann R. Thomas and Lee H. Harrison and Nancy M. Bennett and Monica M. Farley and Richard R. Facklam and James H. Jorgensen and John M. Besser and Elizabeth R. Zell and Anne Schuchat and Cynthia G. Whitney},
  journal={The New England journal of medicine},
  year={2006},
  volume={354 14},
  pages={1455-63}
}
BACKGROUND Five of seven serotypes in the pneumococcal conjugate vaccine, introduced for infants in the United States in 2000, are responsible for most penicillin-resistant infections. We examined the effect of this vaccine on invasive disease caused by resistant strains. METHODS We used laboratory-based data from Active Bacterial Core surveillance to measure disease caused by antibiotic-nonsusceptible pneumococci from 1996 through 2004. Cases of invasive disease, defined as disease caused by… CONTINUE READING
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