Effect of intrapulmonary tetrahydrocannabinol administration in humans

@article{Zuurman2008EffectOI,
  title={Effect of intrapulmonary tetrahydrocannabinol administration in humans},
  author={Lineke Zuurman and Christine Roy and R C Schoemaker and Arno Hazekamp and Jan den Hartigh and Jcme Bender and Robert Verpoorte and JL Pinquier and AF Cohen and J. M. A. van Gerven},
  journal={Journal of Psychopharmacology},
  year={2008},
  volume={22},
  pages={707 - 716}
}
This randomised, double-blind, placebo-controlled, cross-over study was designed to identify which pharmacodynamic parameters most accurately quantify the effects of delta-9-Tetrahydrocannabinol (THC), the predominantly psychoactive component of cannabis. In addition, we investigated the acceptability and usefulness of a novel mode of intrapulmonary THC administration using a Volcano® vaporizer and pure THC instead of cannabis. Rising doses of THC (2, 4, 6 and 8 mg) or vehicle were administered… 

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