Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial.

@article{Massaga2003EffectOI,
  title={Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial.},
  author={Julius J. Massaga and Andrew Yona Kitua and Martha M. Lemnge and Jumaa A Akida and Lincoln N Malle and Anita Mandrup R\onn and Thor G. Theander and I B Christian Bygbjerg},
  journal={Lancet},
  year={2003},
  volume={361 9372},
  pages={1853-60}
}
BACKGROUND Malaria is a major cause of infant morbidity and mortality in sub-Saharan Africa, and is often complicated by severe anaemia. Resistance of Plasmodium falciparum to most affordable antimalarial drugs is an impediment to intermittent chemotherapy. We investigated the effect of presumptive intermittent treatment with amodiaquine and daily iron supplementation in infants on malarial fevers and anaemia, in a holoendemic area of Tanzania where malaria is largely resistant to chloroquine… CONTINUE READING
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