Effect of interbreath fluctuations on characterizing exercise gas exchange kinetics.

@article{Lamarra1987EffectOI,
  title={Effect of interbreath fluctuations on characterizing exercise gas exchange kinetics.},
  author={Norman Lamarra and Brian Whipp and Susan A. Ward and Karlman Wasserman},
  journal={Journal of applied physiology},
  year={1987},
  volume={62 5},
  pages={2003-12}
}
Breathing has inherent irregularities that produce breath-to-breath fluctuations ("noise") in pulmonary gas exchange. These impair the precision of characterizing nonsteady-state gas exchange kinetics during exercise. We quantified the effects of this noise on the confidence of estimating kinetic parameters of the underlying physiological responses and hence of model discrimination. Five subjects each performed eight transitions from 0 to 100 W on a cycle ergometer. Ventilation, CO2 output, and… CONTINUE READING
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