Effect of interaction between adherence to a Mediterranean diet and the methylenetetrahydrofolate reductase 677C-->T mutation on homocysteine concentrations in healthy adults: the ATTICA Study.

@article{Dedoussis2004EffectOI,
  title={Effect of interaction between adherence to a Mediterranean diet and the methylenetetrahydrofolate reductase 677C-->T mutation on homocysteine concentrations in healthy adults: the ATTICA Study.},
  author={George V. Z. Dedoussis and Demosthenes B. Panagiotakos and Christina A Chrysohoou and Christos H Pitsavos and Antonis D Zampelas and Despoina M Choumerianou and Christodoulos Stefanadis},
  journal={The American journal of clinical nutrition},
  year={2004},
  volume={80 4},
  pages={849-54}
}
BACKGROUND Dietary and genetic factors may influence the effect of raised homocysteine concentrations on coronary artery disease risk. OBJECTIVE We evaluated the effect of the interaction between adoption of a Mediterranean diet and the methylenetetrahydrofolate reductase gene (MTHFR) 677C-->T mutation on homocysteine concentrations in healthy adults participating in the ATTICA study. DESIGN We studied demographic, lifestyle, clinical, biochemical, and genetic information from 322 men (x… CONTINUE READING
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