Effect of intensive lipid lowering with atorvastatin on renal function in patients with coronary heart disease: the Treating to New Targets (TNT) study.

@article{Shepherd2007EffectOI,
  title={Effect of intensive lipid lowering with atorvastatin on renal function in patients with coronary heart disease: the Treating to New Targets (TNT) study.},
  author={James George Shepherd and John J. P. Kastelein and Vera A. Bittner and Prakash C. Deedwania and Andrei Breazna and Stephen Dobson and Daniel J. Wilson and Andrea L Zuckerman and Nanette K Wenger},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2007},
  volume={2 6},
  pages={1131-9}
}
BACKGROUND AND OBJECTIVES Data suggest that atorvastatin may be nephroprotective. This subanalysis of the Treating to New Targets study investigated how intensive lipid lowering with 80 mg of atorvastatin affects renal function when compared with 10 mg in patients with coronary heart disease. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A total of 10,001 patients with coronary heart disease and LDL cholesterol levels of <130 mg/dl were randomly assigned to double-blind therapy with 10 or 80… CONTINUE READING
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Impact of aggressive treatment with atorvastatin on renal function in managed care patients with coronary heart disease: The ALLIANCE study

  • M Koren, M Davidson
  • J Clin Lipidol
  • 2007
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