Effect of insulin therapy on metabolic fate of apolipoprotein B-containing lipoproteins in NIDDM.

@article{Taskinen1990EffectOI,
  title={Effect of insulin therapy on metabolic fate of apolipoprotein B-containing lipoproteins in NIDDM.},
  author={Marja Riitta Taskinen and Christopher J. Packard and James Michael Shepherd},
  journal={Diabetes},
  year={1990},
  volume={39 9},
  pages={1017-27}
}
Non-insulin-dependent diabetic (NIDDM) subjects exhibit abnormalities in their plasma lipid and lipoprotein profiles that increase the risk of ischemic heart disease. This study was designed to examine the metabolic behavior of very-low-density (VLDL), intermediate-density (IDL), and low-density (LDL) lipoproteins in NIDDM patients before treatment and after 4 wk of insulin therapy. Basal turnover studies of 131I-labeled VLDL1 (svedberg units [Sf] 60-400) and 131I-labeled VLDL2 (Sf 20-60… CONTINUE READING

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