Effect of insulin on system A amino acid transport in human skeletal muscle.

@article{Bonadonna1993EffectOI,
  title={Effect of insulin on system A amino acid transport in human skeletal muscle.},
  author={R. Bonadonna and M. Saccomani and C. Cobelli and R. DeFronzo},
  journal={The Journal of clinical investigation},
  year={1993},
  volume={91 2},
  pages={
          514-21
        }
}
Transmembrane transport of neutral amino acids in skeletal muscle is mediated by at least four different systems (system A, ASC, L, and Nm), and may be an important target for insulin's effects on amino acid and protein metabolism. We have measured net amino acid exchanges and fractional rates of inward (k(in), min-1) and outward (kout, min-1) transmembrane transport of 2-methylaminoisobutyric acid (MeAIB, a nonmetabolizable amino acid analogue, specific for system A amino acid transport) in… Expand
Effects of insulin and exercise on amino acid transport in rat skeletal muscle.
  • P. A. King
  • Biology, Medicine
  • The American journal of physiology
  • 1994
Transport of carbon-11-methionine is enhanced by insulin.
In vivo muscle amino acid transport involves two distinct processes.
Amino acid uptake in the skeletal muscle measured using [11C]methylaminoisobutyrate (MEAIB) and PET
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