Effect of insulin infusion on spillover of meal-derived fatty acids.

@article{Muthusamy2012EffectOI,
  title={Effect of insulin infusion on spillover of meal-derived fatty acids.},
  author={Kalpana Muthusamy and Robert H. Nelson and Ekta Singh and Danielle T. Vlazny and Almira Smailovic and John M. Miles},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2012},
  volume={97 11},
  pages={
          4201-5
        }
}
CONTEXT Spillover of chylomicron triglyceride fatty acids directly into the circulation as free fatty acids (FFAs) during lipoprotein lipase hydrolysis may contribute to the elevated total FFAs seen in insulin-resistant states. OBJECTIVE The objective of the study was to determine whether spillover is regulated by rates of intracellular lipolysis, we studied overweight and obese nondiabetic subjects (n = 7) on two occasions, during infusion of saline and insulin. DESIGN During insulin… CONTINUE READING
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