Effect of injection time on postictal SPET perfusion changes in medically refractory epilepsy

  title={Effect of injection time on postictal SPET perfusion changes in medically refractory epilepsy},
  author={Robert A. Avery and Susan S. Spencer and Marianna V. Spanaki and Maria Corsi and John P. Seibyl and I. George Zubal},
  journal={European Journal of Nuclear Medicine},
Single-photon emission tomography (SPET) brain imaging in epilepsy has become an increasingly important noninvasive tool in localizing the epileptogenic site. Ictal SPET demonstrates the highest localization sensitivity as compared with postictal and interictal SPET. While ictal SPET consistently reveals hyperperfusion at the epileptogenic site, postictal SPET reveals either hyper- or hypoperfusion depending on the timing of radiopharmaceutical injection. Much discussion in the literature… CONTINUE READING
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