Effect of infliximab in progressive neuro-Behçet's syndrome.

@article{Kikuchi2008EffectOI,
  title={Effect of infliximab in progressive neuro-Behçet's syndrome.},
  author={Hirotoshi Kikuchi and Kaori Aramaki and Shunsei Hirohata},
  journal={Journal of the neurological sciences},
  year={2008},
  volume={272 1-2},
  pages={99-105}
}
Recent studies have shown the beneficial effect of infliximab in ocular manifestation of Behçet's disease. The current studies examined the efficacy of infliximab in progressive neuro-Behçet's syndrome (NB) refractory to methotrexate (MTX). Five male patients with progressive NB with sustained elevation of cerebrospinal fluid (CSF) IL-6 (over 20 pg/ml) despite administration of MTX and steroid, were given intravenous infusion of 5 mg/kg infliximab at weeks 0, 2, 6, and 14 with MTX (10-17.5 mg… CONTINUE READING

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