Effect of inflation of the lung on different parts of pulmonary vascular bed.

@article{Howell1961EffectOI,
  title={Effect of inflation of the lung on different parts of pulmonary vascular bed.},
  author={James B. Howell and Solbert Permutt and D F Proctor and Richard L. Riley},
  journal={Journal of applied physiology},
  year={1961},
  volume={16},
  pages={
          71-6
        }
}
In excised lungs of dogs, the static pressure-volume characteristics of the vascular bed were determined with the vessels filled with dextran and again after replacement of the dextran with kerosene. Whereas the dextran was distributed throughout the entire vascular bed, the kerosene was distributed only in relatively large vessels due to interfacial tension. Volume-pressure curves obtained with kerosene were markedly different from those obtained with dextran. Utilizing both types of volume… 

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