Effect of inflammatory agents and interleukin 1 on iron and zinc metabolism.

@article{Klasing1984EffectOI,
  title={Effect of inflammatory agents and interleukin 1 on iron and zinc metabolism.},
  author={Kirk C. Klasing},
  journal={The American journal of physiology},
  year={1984},
  volume={247 5 Pt 2},
  pages={R901-4}
}
Injection of either sheep red blood cells (SRBC), Escherichia coli, endotoxin, starch, or Sephadex into chicks significantly decreased plasma iron and zinc concentrations. After injection of E. coli or SRBC, plasma zinc was decreased maximally by 52% at 12 h and 15.7% at 48 h, respectively. A second exposure to SRBC or E. coli did not further decrease plasma iron or zinc. Injection of a crude preparation of interleukin 1 isolated from endotoxin-stimulated peritoneal monocytes induced… CONTINUE READING

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