Effect of induced fever on serum iron and ferritin concentrations in man.

  title={Effect of induced fever on serum iron and ferritin concentrations in man.},
  author={Ronald J. Elin and Sheldon M. Wolff and Clement A. Finch},
  volume={49 1},
Previous reports have shown that endotoxin decreases serum iron in experimental animals. In this study fever was produced in nine female and nine male normal subjects in order to define the temporal and quantitative changes in serum iron and ferritin concentrations. Six volunteers were randomly given bacterial endotoxin (5 ng/kg) or saline intravenously and received the alternative compound a week later. Serial blood samples were drawn at 4-hr intervals for a 24-hr period, beginning when the… CONTINUE READING

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