Effect of indomethacin on the level of arachidonic acid in an experimantal model of neurotrauma

@inproceedings{Pantovi2002EffectOI,
  title={Effect of indomethacin on the level of arachidonic acid in an experimantal model of neurotrauma},
  author={Radojka Pantovi{\'c} and Pero Dragani{\'c} and Branka Blagovi{\'c} and Vesna Manova Erakovi{\'c} and Ante Simoni{\'c} and {\vC}edomila Milin},
  year={2002}
}
Introduction: Fatty acids are essential components of membrane phospholipids, having therefore an important role in maintaining the structure and a function of cell membranes. Accumulation of free arachidonic acid, C20:4,a precursor of prostaglandins and leukotriens, is an indicator of nervous cell damage caused by neurotrauma. In this study we followed the effect ofindomethacin, a potent inhibitor of endogenous prostaglandin synthesis, on the level of arachidonic acid in an experimental model… CONTINUE READING