Effect of indomethacin and prostaglandin F2 alpha on incorporation of [3H]uridine by preimplantation mouse embryo.

Abstract

Indomethacin, an inhibitor of prostaglandin synthesis, depressed the incorporation of [3H]uridine into RNA of mouse preimplantation embryo, when it was injected in vivo or added in vitro. In contrast, prostaglandin F2 alpha decreased the inhibitory effect of indomethacin, when it was added in vitro with indomethacin. The results of these experiments suggest… (More)

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@article{Uehara1984EffectOI, title={Effect of indomethacin and prostaglandin F2 alpha on incorporation of [3H]uridine by preimplantation mouse embryo.}, author={Shin-ichi Uehara and Claude A. Villee and Hiroshi Hoshiai}, journal={The Tohoku journal of experimental medicine}, year={1984}, volume={143 3}, pages={319-26} }