Effect of immune complex-containing sera from patients with rheumatic diseases on thromboplastin activity of monocytes.

Abstract

Monocytes isolated from peripheral blood of patients with various rheumatic diseases and circulating immune complexes (IC) developed a significantly higher thromboplastin (tissue factor) activity than normal cells when cultured in vitro without inducers, but normal cells responded more strongly with thromboplastin production upon stimulation with IC or… (More)

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