Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.

@article{Trappe2002EffectOI,
  title={Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.},
  author={Todd A Trappe and Faber White and Charles Paul Lambert and Denis C{\'e}sar and Marc K Hellerstein and William J Evans},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2002},
  volume={282 3},
  pages={
          E551-6
        }
}
  • T. Trappe, F. White, W. Evans
  • Published 1 March 2002
  • Medicine
  • American journal of physiology. Endocrinology and metabolism
We examined the effect of two commonly consumed over-the-counter analgesics, ibuprofen and acetaminophen, on muscle protein synthesis and soreness after high-intensity eccentric resistance exercise. Twenty-four males (25 +/- 3 yr, 180 +/- 6 cm, 81 +/- 6 kg, and 17 +/- 8% body fat) were assigned to one of three groups that received either the maximal over-the-counter dose of ibuprofen (IBU; 1,200 mg/day), acetaminophen (ACET; 4,000 mg/day), or a placebo (PLA) after 10-14 sets of 10 eccentric… 

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