Effect of i.v. ketamine in combination with epidural bupivacaine or epidural morphine on postoperative pain and wound tenderness after renal surgery.

@article{Ilkjaer1998EffectOI,
  title={Effect of i.v. ketamine in combination with epidural bupivacaine or epidural morphine on postoperative pain and wound tenderness after renal surgery.},
  author={S Ilkjaer and Lone Nikolajsen and Troels Martin Hansen and Mogens Wernberg and Jannick Brennum and J\orgen Berg Dahl},
  journal={British journal of anaesthesia},
  year={1998},
  volume={81 5},
  pages={707-12}
}
We studied 60 patients undergoing operation on the kidney with combined general and epidural anaesthesia, in a double-blind, randomized, controlled study. Patients were allocated to receive a preoperative bolus dose of ketamine 10 mg i.v., followed by an i.v. infusion of ketamine 10 mg h-1 for 48 h after operation, or placebo. During the first 24 h after surgery, all patients received 4 ml h-1 of epidural bupivacaine 2.5 mg ml-1. From 24 to 48 h after operation, patients received epidural… CONTINUE READING

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