Effect of hypoxic-ischemic injury on serine palmitoyltransferase activity in the developing rat brain.

Abstract

BACKGROUND Sphingolipid metabolism is strongly associated with central nervous system myelination. Ceramide is the most active of the sphingolipid metabolites. On the basis of ceramide biosynthesis indicated by serine palmitoyltransferase activity and cerebroside generated by ceramide, the evaluation of serine palmitoyltransferase activity in developing… (More)
DOI: 10.1159/000164217

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