Effect of hypoxia on tyrosine and tryptophan hydroxylation in unanaesthetized rat brain.

@article{Davis1973EffectOH,
  title={Effect of hypoxia on tyrosine and tryptophan hydroxylation in unanaesthetized rat brain.},
  author={John Newsom Davis and A. Carlsson},
  journal={Journal of neurochemistry},
  year={1973},
  volume={20 3},
  pages={
          913-5
        }
}
The Tyrosine and tryptophan hydroxylase enzymes have been proposed as rate-limiting steps in the biosynthesis of catecholamines and 5-hydroxytryptamine (5-HT), respectively; thus under normal physiological conditions the rate of amine synthesis appears to be controlled by the activity of these hydroxylase enzymes (see Udenfriend, 1966; Lovenberg, Jequier and Sjoerdsma, 1968). Subtle changes in neuronal activity may result not in changes in the levels of the amine neurotransmitters, but rather… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

The Mammalian Carotid Body

  • Advances in Anatomy Embryology and Cell Biology
  • 1987
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Pathophysiology of Cerebral Energy Metabolism

Bogomir B. Mrsulja, Lj. M. Rakić, Igor Klatzo, Maria Spatz
  • Springer US
  • 1979
VIEW 10 EXCERPTS
CITES METHODS, BACKGROUND & RESULTS
HIGHLY INFLUENCED

Hypoxia. 3. Hypoxia and neurotransmitter synthesis.

  • American journal of physiology. Cell physiology
  • 2011
VIEW 1 EXCERPT
CITES BACKGROUND