Effect of hypoxia on the hypopnoeic and apnoeic threshold for CO(2) in sleeping humans.

@article{Xie2001EffectOH,
  title={Effect of hypoxia on the hypopnoeic and apnoeic threshold for CO(2) in sleeping humans.},
  author={Ailiang Xie and James B Skatrud and Jerome A. Dempsey},
  journal={The Journal of physiology},
  year={2001},
  volume={535 Pt 1},
  pages={269-78}
}
1. Rhythmic breathing during sleep requires that P(CO2) be maintained above a sensitive hypocapnic apnoeic threshold. Hypoxia causes periodic breathing during sleep that can be prevented or eliminated with supplemental CO(2). The purpose of this study was to determine the effect of hypoxia in changing the difference between the eupnoeic P(CO2) and the P(CO2) required to produce hypopnoea or apnoea (hypopnoea/apnoeic threshold) in sleeping humans. 2. The effect of hypoxia on eupnoeic end-tidal… CONTINUE READING
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