Effect of hypoxia on circulating levels of retina-specific messenger RNA in type 2 diabetes mellitus.

@article{Wong2008EffectOH,
  title={Effect of hypoxia on circulating levels of retina-specific messenger RNA in type 2 diabetes mellitus.},
  author={Amy Wong and Simon Merritt and Asif N Butt and Adrian E. Williams and Ramasamyiyer Swaminathan},
  journal={Annals of the New York Academy of Sciences},
  year={2008},
  volume={1137},
  pages={243-52}
}
Previously it was shown that the circulating rhodopsin mRNA level was higher in diabetic retinopathy (DR). Recent evidence suggests that hypoxia may also be associated with DR. The aim of this study was to investigate the effect of oxygen desaturation on circulating retina-specific mRNA in type 2 diabetic patients. Thirty-five type 2 diabetic patients underwent overnight oximetry. Two parameters from oximetry were used to measure oxygen desaturation: the number of times per hour the oxygen… CONTINUE READING

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