Effect of hypoxia on adaptation of the pulmonary circulation to extra-uterine life in the pig.

@article{Haworth1982EffectOH,
  title={Effect of hypoxia on adaptation of the pulmonary circulation to extra-uterine life in the pig.},
  author={Sheila. G. Haworth and Alison A Hislop},
  journal={Cardiovascular research},
  year={1982},
  volume={16 6},
  pages={293-303}
}
Pigs were exposed to hypoxia for 2 to 5 days, at ages ranging from bith to 2 weeks. The effect of hypoxia on structural adaptation of the pulmonary arterial circulation to extra-uterine life was studied by applying quantitative morphometric techniques to the injected autopsy lung specimens. In animals exposed to hypoxia from birth, the reduction in arterial muscularity, and increase in size and number which normally takes place after, began to occur, but the process was arrested by exposure to… CONTINUE READING