Effect of hypoxia-inducible factor-1/vascular endothelial growth factor signaling pathway on spinal cord injury in rats

@inproceedings{Chen2017EffectOH,
  title={Effect of hypoxia-inducible factor-1/vascular endothelial growth factor signaling pathway on spinal cord injury in rats},
  author={Hailong Chen and Junjie Li and Shuhan Liang and Bin Lin and Qi Peng and Peng Zhao and Jiawei Cui and Yaojian Rao},
  booktitle={Experimental and therapeutic medicine},
  year={2017}
}
The aim of the present study was to evaluate the expression of vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 (HIF-1), and to investigate the role of the HIF-1/VEGF signaling pathway following spinal cord injury (SCI). A total of 90 12-week-old Sprague Dawley rats were randomly divided into the following three groups: Sham group (operation without SCI); control group (SCI without ML228 treatment); and treatment group (SCI receiving ML228 treatment). ML228 was… CONTINUE READING