Effect of hypoxia and norepinephrine on cytoplasmic free Ca2+ in pulmonary and cerebral arterial myocytes.

@article{Vadula1993EffectOH,
  title={Effect of hypoxia and norepinephrine on cytoplasmic free Ca2+ in pulmonary and cerebral arterial myocytes.},
  author={M S Vadula and Jack G. Kleinman and Jane Madden},
  journal={The American journal of physiology},
  year={1993},
  volume={265 6 Pt 1},
  pages={L591-7}
}
The fluorescent calcium indicator, fura 2, was used to test whether contraction of primary cultured smooth muscle cells (SMC) from small pulmonary arteries in response to hypoxia and the relaxation by large pulmonary and cerebral artery SMC were mediated by changes in cytoplasmic free Ca2+ (Ca2+c). Because SMC from large pulmonary and cerebral arteries contract to norepinephrine (NE), Ca2+c levels during NE exposure were measured to determine if they differed from those seen with hypoxia. Under… CONTINUE READING
41 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

Similar Papers

Loading similar papers…