Effect of hypothyroidism induced by propylthiouracil on ovarian function and structure in offspring from treated mothers (Rats).

@article{Zertashia2002EffectOH,
  title={Effect of hypothyroidism induced by propylthiouracil on ovarian function and structure in offspring from treated mothers (Rats).},
  author={Akram Zertashia and Samina Jalali and L. Faheem Ahmad and Asma Mirza},
  journal={The Journal of experimental zoology},
  year={2002},
  volume={293 4},
  pages={407-13}
}
The aim of the present study was to investigate the effects of hypothyroidism induced during the pre- and postnatal periods of life on ovarian function and structure in offspring (pups) 120 days of age. Three groups were used. In the prenatal group, treatment was given from conception to parturition. In the postnatal group, treatment was given from parturition to 25 days postpartum. Hypothyroidism was induced by administration of 0.1% 6-n-propyl-2-thiouracil (PTU) in the drinking water of… CONTINUE READING