Effect of hypophysectomy and growth hormone administration on somatostatin content in the rat hypothalamus.

@article{Kanatsuka1979EffectOH,
  title={Effect of hypophysectomy and growth hormone administration on somatostatin content in the rat hypothalamus.},
  author={Azuma Kanatsuka and Hirofumi Makino and Youko Matsushima and Masaaki Osegawa and Machiko Yamamoto and A. Kumagai},
  journal={Neuroendocrinology},
  year={1979},
  volume={29 3},
  pages={
          186-90
        }
}
The effect of hypophysectomy and bovine GH administration on somatostatin (SRIF) content in the rat hypothalamus was investigated. SRIF content was determined by a specific radioimmunoassay method described elsewhere. The total SRIF content of the rat hypothalamus as well as its content per milligram wet weight had decreased 4 weeks after hypophysectomy but was restored significantly in those rats which were subjected to bovine GH administration for 7 days 3 weeks after hypophysectomy… CONTINUE READING
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