Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs

@inproceedings{Holms2015EffectOH,
  title={Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs},
  author={Carla Augusto Holms and Denise Aya Otsuki and Marcia Aparecida Portela Kahvegian and Cristina de Oliveira Massoco and Denise T. Fantoni and Paulo Sampaio Gutierrez and Juarez Coimbra Ormonde Junior},
  booktitle={Clinics},
  year={2015}
}
OBJECTIVES Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory effects of administering a single intravenous dose of 7.5% hypertonic saline in an experimental model of acute lung injury induced by hydrochloric acid. METHODS Thirty-two pigs were anesthetized and randomly allocated into the following four… CONTINUE READING

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